Calendula officinalis, commonly known as pot marigold, is the member of the Asteraceae family and plays an important role in addressing various health issues. It has been traditionally used to alleviate inflammation, treat ulcers, and resolve skin and digestive troubles, as well as to ease nervousness and insomnia, among other conditions. The plant contains the variety of compounds, such as lipids, terpenoids, carotenoids, coumarins, and quinones. Many studies have confirmed its medicinal benefits, highlighting its anti-inflammatory, healing, and regenerative properties, along with antimicrobial, anticancer, antigenotoxic, and genotoxic effects. Additionally, it has hepatoprotective, neuroprotective, and cardioprotective qualities, as well as gastroprotective, antioxidant, spasmogenic, and spasmolytic activities. Calendula also shows antiprotozoal, anthelmintic, acaricidal, antiviral, anti-aging, photoprotective, and immunostimulant effects.Clinical trials have highlighted its efficacy for conditions such as ulcers, radiodermatitis, burn wounds, oropharyngeal mucositis, plague, and gingivitis, with no reported toxicity. Due to these properties, calendula is incorporated into various medicines and finds a place in the food industry as its flowers are edible, suitable for fresh salads or dried for dyeing purposes.This study aims to provide a comprehensive overview of pot marigold, coverning its distribution,botanical characyeristics, cultivation methods, traditional applications, phytochemicals, phytochemistry, and pharmacological actions.
